Clozapine: more side effects but still the best antipsychotic.
نویسندگان
چکیده
منابع مشابه
گزارش یک مورد آگرانولوسیتوز بدنبال مصرف کلوزاپین
Introduction : clozapine is the first effective antipsychotic drug with the least extra pyramidal side effects and more agranulocytosis than other standard neuroleptics. Granolocytopenia or agranulocytosis occurs in 1 to 2 percent of all patients treated with clozapine. agranulocytosis due to clozapine is a fatal disorder that requires immediate clinical intervention. Method : this paper re...
متن کاملکلوزاپین: انقلابی جدید در درمان شیزوفرنی
Clozapine is the first antipsycotic drug with a great efficacy. Thirty to fifty percent of treatment-resistant schizophrenics markedly improved with clozapine. Approximately, 25% of long-term patients, treated with clozapine, could be discharged. This improvement included negative as well as positive symptom areas. Clozapine produced no extrapyramidal side effects. Tardive dyskinesia, a major s...
متن کاملبررسی عوارض جانبی کلوزاپین در مراحل مختلف درمان در نمونه ای از بیماران اسکیزوفرنیک مقاوم به درمان
Background and purpose:Çlozapine is an antipsychotic with the least extrapyramidal side effects and more agranulositosis than typical antipsychotics. Çlozapine has the unique effects on the treatment-resistant schizophrenia but with threatening side effects on the patients. Thus we did this prospective study in order to identufy the side effects of clozapine in Ïranian treatment-resistant sch...
متن کاملClozapine-induced Gastrointestinal Hypomotility--New Objective Evidence for an Underestimated Side-effect.
Available online 27 February 2016 serum levels and (3) that this hypomotilitywas not reported by patients by themeans of subjective constipation symptoms. Remarkably, CTTs in clozapine were four times longer than for other antipsychotics or population norms and 4 of 5 clozapine-treated patients showed clear Clozapine is still the most effective antipsychotic drug in the manhypomotility (Every-P...
متن کاملFocus on clozapine: a new explanation for its atypical character.
Although atypical antipsychotics have become the treatment of choice for schizophrenia, there is no consensus on the mechanisms of action leading to the ‘atypical ’ character of these medications. Atypical antipsychotics are often referred to as ‘novel’, even though the prototypical antipsychotic of this series, clozapine, has been introduced into clinics for decades. Clozapine was found effect...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of clinical psychiatry
دوره 71 8 شماره
صفحات -
تاریخ انتشار 2010